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目的了解肝炎肝硬化患者肝功能检验的临床意义。方法随机选取2013年8月-2015年6月宁夏某医院收治的36例肝炎肝硬化患者为观察组,经B超、实验室及临床检查确诊为肝炎肝硬化,根据Child-Pugh分级标准,其中Child A级17例、Child B级10例、Child C级9例;另选取36例健康者为对照组,两组均给予肝功能检验并对检验结果进行比较分析。结果(1)观察组总胆汁酸(TBA)水平高于对照组,但观察组血清胆固醇(CHO)、白蛋白(ALB)、血清胆碱酯酶(CHE)水平低于对照组,差异具有统计学意义(P<0.05)。(2)肝炎肝硬化患者Child A级至Child C级的CHE、ALB、CHO水平值持续下降,TBA水平值持续上升,差异具有统计学意义(P<0.05)。结论对肝炎肝硬化患者进行肝功能检验,可对病情作出更准确的评估,有利于肝炎肝硬化的诊断与疗效。
Objective To understand the clinical significance of liver function tests in patients with liver cirrhosis. Methods Thirty-six patients with hepatitis cirrhosis admitted from Ningxia Hospital from August 2013 to June 2015 were randomly selected. The liver cirrhosis was diagnosed by B-ultrasound, laboratory and clinical examination. According to Child-Pugh grading criteria, There were 17 cases of Child A, 10 cases of Child B and 9 cases of Child C. The other 36 cases were selected as control group. Both groups were given liver function tests and the results were compared. Results (1) The total bile acid (TBA) in the observation group was higher than that in the control group, but the levels of serum cholesterol (CHO), albumin (ALB) and serum cholinesterase (CHE) in the observation group were lower than those in the control group Significance (P <0.05). (2) The levels of CHE, ALB and CHO in Child A-to-Child C-level patients with hepatitis cirrhosis continued to decrease, while the TBA levels continued to rise, the difference was statistically significant (P <0.05). Conclusions The liver function test in patients with cirrhosis of liver can make a more accurate assessment of the condition, which is benefit to the diagnosis and curative effect of hepatitis cirrhosis.