虫卵肉芽肿是血吸虫病性肝纤维性变的先驱,而淋巴细胞和巨噬细胞则是形成纤维化以前肉芽肿的主要细胞成分。已有文献报道,淋巴细胞在体外产生可溶性物质,后者可抑制或加强成纤维细胞的增殖和刺激胶原的合成。巨噬细胞也可影响成纤维细胞的生长和蛋白的合成。为了阐明虫卵肉芽肿与肝纤 Egg granuloma is a precursor to schistosomiasis-induced liver fibrosis, whereas lymphocytes and macrophages are the major cellular components that form granulomas prior to fibrosis. It has been reported in the literature that lymphocytes produce soluble substances in vitro, which can inhibit or enhance the proliferation of fibroblasts and stimulate the synthesis of collagen. Macrophages can also affect fibroblast growth and protein synthesis. To clarify the egg granuloma and liver fibrosis