[目的]总结分析我院近3年中、西药临床应用中药物不良反应(ADR)的发生情况,促进临床合理用药。[方法]对300例ADR报表进行回顾性分类统计分析。[结果]ADR涉及的药品种类繁多,其中以抗感染药居首位,中药制剂次之;ADR以皮肤及其附件损害最为常见;静脉给药方式占多数。[结论]加强ADR监测工作,重视ADR,合理用药,减少或避免ADR的发生,提高临床用药的安全性。 [Objective] To summarize and analyze the incidence of adverse drug reaction (ADR) in the clinical application of western medicine in our hospital in the past 3 years and to promote the rational use of clinical medicine. [Methods] Retrospective classification and statistical analysis of 300 ADR reports. [Results] There were many kinds of drugs involved in ADR, of which anti-infectives ranked first, followed by traditional Chinese medicine preparations; ADR was the most common damage to skin and its appendages; [Conclusion] To strengthen the monitoring of ADR, pay attention to ADR, use medicine rationally, reduce or avoid the occurrence of ADR and improve the safety of clinical medication.