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目的:观察治疗消化性溃疡药物联合小剂量抗焦虑、抗抑郁药物辅助治疗消化性溃疡的疗效,给予临床指导。方法:选取60例确诊为消化性溃疡患者,随机分为治疗组和对照组各30例,两组均常规给予抑制胃酸、保护胃粘膜、控制幽门螺旋杆菌感染,治疗组在此基础上,给予小剂量抗焦虑抑郁药,直至出院后1个月为止。两组均在服药后1月末、2月末进行疗效复查,比较两组的疗效。结果:两组在治疗1个月后,治疗组总有效率为76.67%,对照组总有效率为46.67%,治疗组疗效明显高于对照组,P<0.01;治疗2个月后治疗组总有效率为93.33%,对照组总有效率为70.00%,两组总有效率较治疗后1个月均有上升,治疗组疗效明显高于对照组,P<0.01。结论:消化性溃疡患者大都有一定的心理障碍,通过联合小剂量精神科药物,能够辅助治疗消化性溃疡疾病,提高疗效,促进早日康复,值得临床推广。
OBJECTIVE: To observe the curative effect of peptic ulcer drug combined with low-dose anxiolytic and anti-depressant drugs in the treatment of peptic ulcer and to give clinical guidance. Methods: Sixty patients diagnosed as peptic ulcer were randomly divided into treatment group (n = 30) and control group (n = 30). Both groups were given conventional gastric acid inhibition, gastric mucosa protection and helicobacter pylori infection control. On the basis of this, Low-dose anti-anxiety depression drugs until 1 month after discharge. Two groups were in the end of January after treatment, the end of February to review the efficacy, the efficacy of the two groups were compared. Results: The total effective rate was 76.67% in the treatment group and 46.67% in the control group after 1 month of treatment. The therapeutic effect in the treatment group was significantly higher than that in the control group, P <0.01. After 2 months of treatment, the total effective rate was 76.67% The effective rate was 93.33%. The total effective rate of the control group was 70.00%. The total effective rate of both groups increased compared with that of the control group one month after treatment. The therapeutic effect of the treatment group was significantly higher than that of the control group (P <0.01). Conclusion: Most patients with peptic ulcer have certain psychological disorders. Combined with small dose of psychotropic drugs, it can assist in the treatment of peptic ulcer disease, improve the curative effect and promote early recovery, which is worthy of clinical promotion.