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目的：观察氟罗沙星对照氧氟沙星治疗肺部感染的疗效。方法：３８例痰菌培养阳性的肺部感染病人分２组，治疗组２２例（男性１３例，女性９例，年龄６４±ｓ９ａ）用氟罗沙星０．４ｇ，ｐｏ，ｑｄ×６ｄ。对照组１６例（男性１１例，女性５例，年龄６６±７ａ）用氧氟沙星０．２ｇ，ｐｏ，ｂｉｄ×６ｄ。结果：前者有效率７７％，菌株清除率７７％。后者分别为７５％和８１％。２组无显著性差异（Ｐ＞０．０５）。结论：氟罗沙星是治疗肺部感染的有效药物，无显著不良反应。
Objective: To observe the efficacy of fleroxacin against ofloxacin in the treatment of pulmonary infection. Methods: Thirty-eight patients with sputum culture-positive pulmonary infection were divided into two groups. Twenty-two patients in the treatment group (13 males and 9 females, age 64 ± s9a) were treated with fleroxacin 0.4g, po, qd × 6d. Control group of 16 patients (11 males and 5 females, age 66 ± 7a) ofloxacin 0.2g, po, bid × 6d. Results: The former was 77% efficient, 77% strain clearance. The latter were 75% and 81% respectively. There was no significant difference between the two groups (P> 0.05). Conclusion: Fleroxacin is an effective drug for the treatment of pulmonary infection without significant adverse reactions.