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目的观察缩宫祛瘀汤经验方联合米非司酮、米索前列醇治疗稽留流产的临床疗效。方法将116例稽留流产患者随机分为两组。对照组给予米索前列醇联合米非司酮治疗,治疗组在对照组治疗基础上加用缩宫祛瘀汤经验方治疗。结果治疗组总有效率显著优于对照组(P<0.01);治疗组胚胎排出时间、用药后阴道出血时间均明显短于对照组,其出血量明显少于对照组(均P<0.05);治疗组不良反应发生率明显低于对照组(P<0.05)。结论缩宫祛瘀汤经验方联合米非司酮、米索前列醇治疗稽留流产疗效确切,利于促进胚胎的排出,缩短阴道出血时间,减少出血量,用药安全性高。
Objective To observe the curative effect of Si Gong Qu Yu Decoction combined with mifepristone and misoprostol in the treatment of missed abortion. Methods 116 cases of missed abortion were randomly divided into two groups. The control group was treated with misoprostol combined with mifepristone, and the treatment group was treated with the prescription of Siyu Quyu Decoction on the basis of the control group. Results The total effective rate in the treatment group was significantly better than that in the control group (P <0.01). The time of excretion and vaginal bleeding in the treatment group were significantly shorter than those in the control group. The bleeding volume in the treatment group was significantly less than that in the control group (all P <0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (P <0.05). Conclusions: Sihouquyu Decoction prescription combined with mifepristone and misoprostol in treatment of missed abortion is effective in promoting embryo excretion, shortening the time of vaginal bleeding and reducing the amount of bleeding, so it is safe to use.