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目的探讨淋巴结原发性上皮样血管内皮瘤(EH)的临床病理学特点及鉴别诊断要点。方法分析1例淋巴结原发性上皮样血管内皮瘤的临床、组织病理学资料,进行常规HE染色及免疫组化检测,并结合文献进行讨论。结果组织学上,肿瘤细胞呈圆形或类圆形上皮样,瘤细胞增生呈乳头状凸向腔内,胞质嗜伊红染,细胞边界不清。免疫组化示肿瘤细胞CD31(+),CD34和FⅧRAg(-)。结论淋巴结原发性上皮样血管内皮瘤是罕见的低度恶性血管性肿瘤,可出现多种组织结构,有一定的特征性,应与淋巴结转移性恶性肿瘤及原发于淋巴结的其他血管源性肿瘤鉴别。
Objective To investigate the clinicopathological features and differential diagnosis of primary epithelial hemangioendothelioma (EH) in lymph nodes. Methods One case of primary epithelial hemangioendothelioma of the lymph node was analyzed by clinical and histopathological data, and routine HE staining and immunohistochemistry were performed. Results Histologically, the tumor cells were round or oval epithelium-like, hyperplasia of tumor cells papillary convex cavity, cytoplasm eosinophilic staining, cell boundaries are unclear. Immunohistochemistry showed that the tumor cells CD31 (+), CD34 and FⅧRAg (-). Conclusion Lymph node primary epithelioid hemangioendothelioma is a rare low grade malignant tumor. It may have many kinds of tissues and structures. It has certain characteristic. It should be associated with lymph node metastatic malignant tumor and other vasogenic origin of lymph node Tumor identification.