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目的:观察鼻咽血管纤维瘤术前放疗加手术治疗的临床疗效。方法:33例患者中,单纯手术者21例,12例手术前2周行60Co放射5~7 d,放射量10~20 Gy。结果:单纯手术者,术中出血250~3 600 ml,平均1 100 ml;放疗加手术者,术中出血200~800 ml,平均450 ml,其差异有统计学意义(P<0.01)。单纯手术者,手术时间为3~6 h,放疗加手术者,手术时间为1~3 h,其差异有统计学意义(P<0.01)。单纯手术者术后复发4例;放疗加手术者术后无复发。结论:放疗后切除鼻咽血管纤维瘤,有利于减少术中出血和术后复发。
Objective: To observe the clinical efficacy of preoperative radiotherapy and surgical treatment of nasopharyngeal angiofibroma. Methods: Among the 33 patients, 21 cases were operated on alone and 12 cases were treated with 60Co for 5 ~ 7 days and 10 ~ 20 Gy after 2 weeks. Results: In the simple operation, the intraoperative bleeding ranged from 250 to 3 600 ml with an average of 1 100 ml. The radiotherapy plus operation showed an intraoperative bleeding of 200 to 800 ml with an average of 450 ml (P <0.01). For simple operation, the operation time was 3 ~ 6 h, radiotherapy plus operation, the operation time was 1 ~ 3 h, the difference was statistically significant (P <0.01). Operative patients after surgery alone 4 cases of recurrence; radiotherapy plus surgery without recurrence. Conclusion: Radiotherapy after nasopharyngeal angiofibroma resection is helpful to reduce intraoperative bleeding and postoperative recurrence.