小儿止咳糖浆中NH_4Cl的含量测定方法,各省标准不同,有银量摩尔法及定氮测定法,但都由于处方中的甘草流浸膏含有NH_3,造成含量偏高。笔者根据NH_3能溶于乙醚而NH_4Cl不溶的原理,参照《江西省药品标准》(1982年版)在用摩尔法测定之前,先用乙醚提取NH_3,除去NH_3干扰,再测定小儿止咳糖浆的含量,并与原方法和用甘草流浸膏对照方法进行比较,取得了较为满意的结果。测定方法 Pediatric cough syrup in the determination of NH_4Cl content, the provincial standards are different, there are silver molar method and determination of nitrogen method, but because of prescription licorice extract containing NH_3, resulting in high levels. According to the principle that NH_3 can dissolve in ether and NH_4Cl is insoluble, referring to the “Jiangxi Province Drug Standards” (1982 edition), before the determination by the molar method, NH_3 was first extracted with ether to remove the interference of NH_3, and then the pediatric cough syrup content was determined Compared with the original method and the liquorice extract control method, satisfactory results were obtained. test methods