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采用酶联免疫吸附试验 (EL ISA)对 2 0 0例不明原因不孕症妇女 (不孕组 )及 4 1例健康孕妇 (对照组 )血清中抗子宫内膜抗体 (EMAb)进行检测。结果显示 :对照组血清 EMAb阳性率 2 .4 % ;不孕组血清 EMAb阳性率 2 8% ,明显高于对照组 (P<0 .0 1)。不孕组中原发不孕患者血清 EMAb阳性率 17.35% ;人流 (吸 /刮宫 )术后继发不孕患者血清 EMAb阳性率高达 37.0 9% ,显著高于原发不孕组。提示 EMAb的产生可能是导致不孕的原因之一 ,而人流术是促使 EMAb产生的一个因素
Serum anti-endometrial antibodies (EMAb) were detected by enzyme-linked immunosorbent assay (ELISA) in 200 unexplained infertility women (infertility group) and 41 healthy pregnant women (control group). The results showed that the positive rate of serum EMAb in control group was 2.4%; the positive rate of serum EMAb in infertility group was 28%, which was significantly higher than that of control group (P <0.01). The positive rate of serum EMAb in infertile patients was 17.35%. The positive rate of serum EMAb was 37.0 9% in patients with secondary infertility after abortion (suction / curettage), which was significantly higher than that of primary infertility patients. Suggesting that the generation of EMAb may be one of the reasons leading to infertility, and abortion is to promote EMAb a factor