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本文观察翼状胬肉手术三种应用丝裂霉素Ｃ的方法对防止术后翼状胬肉复发的作用，采用随机分组方法对８３例１１２眼原发性翼状胬肉进行病例对照研究。丝裂霉素Ｃ的应用方法分别为术中应用（０．４ｍｇ／ｍｌ），术后一周内应用及手术一周后应用（０．２ｍｇ／ｍｌ）。结果：术中应用丝裂霉素Ｃ组翼状胬肉复发率为８．３％，术后一周内应用组复发率为１６．１％，手术一周后应用组为２０．７％，三组间的复发率无统计学差异，对照组为３２．１％，与治疗组比较具有明显统计学差异。术后一周内应用丝裂霉素组角膜创面愈合延迟。结论：翼状胬肉切除术中或术后应用丝裂霉素Ｃ可防止术后复发。术中应用丝裂霉素Ｃ方法简单，不影响角膜创面的愈合。
In this paper, we observed three methods of mitomycin C in the application of mitomycin C to prevent the recurrence of the pterygium. A randomized controlled study was conducted on 83 cases of 112 cases of primary pterygium. Mitomycin C was applied intraoperatively (0.4mg / ml), one week after surgery and one week after surgery (0.2mg / ml). Results: The intraoperative recurrence rate of mitomycin C group was 8.3%, the recurrence rate was 16.1% in one week after operation and 20.7% in one week after operation, Of the recurrence rate was no significant difference in the control group was 32.1%, compared with the treatment group had significant statistical difference. The mitomycin group had a delayed corneal wound healing within one week after operation. Conclusion: Mitomycin C can prevent postoperative recurrence during or after pterygium resection. Intraoperative mitomycin C method is simple, does not affect the corneal wound healing.