我们测定了糖尿病患者血浆内皮素及心钠素的水平,并初步讨论了它们之间的关系.对象和方法(一)对象:糖尿病43例,均符合1985年 WHO诊断标准。男30例,女13例,年龄31～70岁,均属Ⅱ型糖尿病,病史2月～5年,无心、肺、肾、肝等疾病和高血压病,单纯服用降糖药。健康人18名,男13名,女5名,年龄30～70岁,为某单位健康体检人员。(二)方法:晨6～7时空腹采上肢静脉血3ml,置于含1%EDTA 二钠30μl和抑肽酶40μl的试管中混 We measured plasma levels of endothelin and atrial natriuretic peptide in patients with diabetes mellitus and initially discussed the relationship between them.Patients and Methods (a) Subjects: 43 cases of diabetes, all in line with the 1985 WHO diagnostic criteria. 30 males and 13 females, aged 31 to 70 years old, are type II diabetes, history of February to 5 years, no heart, lung, kidney, liver and other diseases and hypertension, simply taking hypoglycemic agents. 18 healthy people, 13 men and 5 women, aged 30 to 70 years old, for a unit of health examination staff. (B) Methods: Morning 6 ~ 7 fasting blood samples taken upper limb venous blood 3ml, placed in 1% EDTA disodium 30μl and aprotinin 40μl tube mixed