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紫草为药典收载临床常用传统中药。它最初记载于《神农本草经》,紫草(RADIX ARNEBIAE)属于紫草科多年生草本植物,药用干燥根,其萘醌类色素、多糖是主要含有的两大类有效成分。由于临床广泛应用,发现它在许多难治性疾病如肿瘤、艾滋病、过敏性紫癜、银屑病等,显现出非常好的治疗效果,已引起广大药物研究工作者的注意,在资源、植化、药效、药动、制剂等方面,展开了不断深入的研究。现仅对笔者所收集到的有关文献资料,针对其实验研究部分作一简要、突出重点的综述。
Lithospermum is used as a pharmacopoeia to collect commonly used traditional Chinese medicines. It was originally recorded in the “Shen Nong’s Materia Medica”. RADIX ARNEBIAE is a perennial herb of the genus Boraginaceae. Its medicinal dry roots, its naphthoquinone pigments and polysaccharides are the two main active ingredients contained. Due to its wide clinical application, it has been found in many difficult-to-treat diseases such as cancer, AIDS, allergic purpura, psoriasis, etc., and has shown very good therapeutic effect, which has attracted the attention of the majority of drug researchers, in terms of resources and phytochemicals. Pharmacodynamics, pharmacokinetics, and preparations have been continuously studied. Only a brief summary of the relevant literature and data collected by the author is given for the experimental research part.