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目的观察益赛普联合甲氨喋呤对类风湿关节炎的疗效。方法将我科门诊30例类风湿关节炎患者分为两组各15例,观察组每周皮下注射益赛普2次,每次25mg,同时每周给予患者1次甲氨喋呤10mg口服;对照组只采取口服甲氨蝶呤的方法,每周1次,每次10mg。3个月后比较两组患者的ACR70、ACR50、ACR20等指标,观察两组疗效。结果观察组各项指标都明显优于对照组。结论甲氨喋呤与益赛普联合治疗类风湿关节炎的效果优于甲氨喋呤单药治疗,有条件者应及早应用。
Objective To observe the curative effect of Yixipu combined with methotrexate on rheumatoid arthritis. Methods Thirty patients with rheumatoid arthritis in our department were divided into two groups of 15 patients. The observation group was subcutaneously injected with 25 mg of ixprofine subcutaneously once per week, while the patients were given methotrexate 10 mg orally once a week. Control group only take oral methotrexate method, once a week, each time 10mg. After 3 months, ACR70, ACR50, ACR20 and other indexes were compared between the two groups to observe the curative effect of the two groups. Results The observation group indicators were significantly better than the control group. Conclusion The combination of methotrexate and etanercept is superior to methotrexate in the treatment of rheumatoid arthritis, and should be applied as soon as possible.