论文部分内容阅读
目的探讨肿瘤坏死因子-(TNF-)在Eales病患者血清中的浓度变化及临床意义。方法用Luminex检测技术检测TNF-在Eales病患病组和健康对照组血清中的浓度值并做统计学分析。结果TNF-在Eales病患病组中的浓度为(23.12±0.79)pg/ml显著高于健康对照组的浓度含量[(12.18±0.29)pg/ml]差异有统计学意义(<0.01)。结论 Eales病患者血清中TNF-的浓度显著升高与Eales病的血管炎、新生血管、玻璃体出血等临床表现有一定的关系。TNF-对Eales病的临床观察预后有一定的临床意义。
Objective To investigate the changes and clinical significance of tumor necrosis factor - (TNF-) in serum of patients with Eales disease. Methods The concentration of TNF-α in the sera of patients with Eales disease and healthy controls was detected by Luminex detection technique and analyzed statistically. Results The concentration of TNF-α in the Eales patient group was significantly higher than that in the healthy control group ([(12.18 ± 0.29) pg / ml] (P <0.01). Conclusion The significant increase of serum TNF-α in patients with Eales disease may be related to the clinical manifestations of vasculitis, neovascularization and vitreous hemorrhage in Eales disease. TNF-a clinical observation of Eales disease prognosis of certain clinical significance.