论文部分内容阅读
目的:探讨大连地区结直肠癌患者的临床病理特征以及近年来的变化趋势。方法:回顾性分析2002年1月—2006年12月经手术病理证实的582例结直肠癌患者,分析其临床病理特征,包括发病年龄、病变部位和病理类型等。结果:60～69岁和70～79岁为结直肠癌高发年龄段(P<0.05);直肠是最常见的发病部位;腺癌是主要的病理类型,其中以中分化腺癌为主。随着年龄的增加,高分化腺癌的构成百分比呈明显上升趋势,低分化腺癌的构成百分比呈明显下降趋势(P<0.05),中分化腺癌的变化趋势不明显。结论:大连地区结直肠癌的高发年龄段为60～79岁。随着年龄的增加,结直肠癌的恶性程度有所下降。
Objective: To investigate the clinicopathological features of colorectal cancer patients in Dalian area and the changing trend in recent years. Methods: A retrospective analysis of 582 patients with colorectal cancer confirmed by surgery and pathology from January 2002 to December 2006 was performed. The clinical and pathological features were analyzed including age of onset, location of lesion and pathological type. Results: The incidence of colorectal cancer was significantly higher in patients aged 60-69 years and 70-79 years (P <0.05). Rectal cancer was the most common site of disease. Adenocarcinoma was the major pathological type, with moderately differentiated adenocarcinoma predominating. With the increase of age, the percentage of well-differentiated adenocarcinoma showed a clear upward trend, the percentage of poorly differentiated adenocarcinoma showed a significant decrease (P <0.05), and the trend of moderately differentiated adenocarcinoma was not obvious. Conclusion: The high incidence of colorectal cancer in Dalian is 60 ~ 79 years old. With age, the malignancy of colorectal cancer has declined.