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为了解正常与重度窒息新生儿出生后肺动脉压力的动态变化。作者对正常新生儿25例，重度窒息新生儿53例，应用二维脉冲多普勒超声心动图，在生后1天，2天，3天以内及7天连续四次测定肺动脉血流射血前期和加速时间比值（PEP／AT）。结果示正常新生儿肺动脉压力随着时间的推延而下降，第1天至第2天下降明显。PEP／AT比值分别为1．10±0．40，0．88±0．13，0．83±0．15，0．78±0．18。重度窒息新生儿生后3天内肺动脉压力明显高于正常新生儿，第1天至第2天和第3天至第7天有两次大幅度下降，至第7天与正常新生儿相似，PEP／AT分别为1．57±0．50，1．27±0．40，1．18±0．49，0．87±0．33。正常新生儿生后暂时性肺动脉压力增高只持续1天，而重度窒息新生儿需要7天左右肺动脉压力才能降至接近正常。
To understand the dynamic changes of pulmonary artery pressure after birth in normal and severe asphyxia neonates. The author of 25 cases of normal newborns, 53 cases of severe neonatal asphyxia, application of two-dimensional pulsed Doppler echocardiography, 1 day after birth, 2 days, 3 days and 7 days continuous determination of pulmonary arterial ejection Proportional and Accelerated Time Ratio (PEP / AT). The results showed that normal neonatal pulmonary artery pressure decreased over time, the first day to the second day decreased significantly. PEP / AT ratios were 1.10 ± 0.40, 0.88 ± 0.13, 0.83 ± 0.15 and 0.78 ± 0.18, respectively. Pulmonary arterial pressure was significantly higher in newborns with severe asphyxia within three days of birth than in normal newborns with two significant decreases from day 1 to day 2 and from day 3 to day 7, similar to normal neonates at day 7, and PEP / AT were 1.57 ± 0.50, 1.27 ± 0.40, 1.18 ± 0.49 and 0.87 ± 0.33, respectively. Temporary newborn after birth, transient pulmonary pressure increased only for 1 day, and severe asphyxia neonatal need about 7 days before pulmonary artery pressure can be reduced to near normal.