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目的 评价内镜粘膜切除术治疗癌前病变和早期食管癌的效果,并对其适应证、手术操作和并发症等进行临床研究。方法 从食管癌高发现场的普查和门诊工作中发现的病例,选择符合内镜粘膜切除适应证者,在镇静麻醉下完成154例内镜粘膜切除术。对术中发生的一些并发症进行了认真观察和处理。结果 完成154例内镜粘膜切除术,发生创面小动脉出血发生18例（11.7％）,食管穿孔2例（1.3％）,经处理后均顺利痊愈。结论 内镜粘膜切除术是治疗食管鳞状细胞原位癌、粘膜内癌和癌前病变的重要治疗方法。
Objective To evaluate the efficacy of endoscopic mucosal resection for the treatment of precancerous lesions and early esophageal cancer and to conduct clinical studies on its indications, surgical procedures and complications. Methods A total of 154 cases of endoscopic mucosal resection under sedation anesthesia were selected from the cases found in the census and outpatient work of esophageal cancer. Some complications occurred during surgery were carefully observed and dealt with. Results A total of 154 cases of endoscopic mucosal resection were performed. Eighteen cases (11.7%) and 2 cases of esophageal perforation (1.3%) developed hemorrhage of wound arteries, which were successfully cured after treatment. Conclusion Endoscopic mucosal resection is an important treatment for esophageal squamous carcinoma in situ, mucosal carcinoma and precancerous lesions.