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原发性骨髓纤维化(AMM)行巨脾切除治疗方法国内少见报道,我们曾收治1例报道如下。病历摘要患者女,47岁。腹部包块渐增大17年。入院时包块已达盆腔,食欲不振,消瘦乏力。近半年牙龈出血,平卧即感气促,被迫半卧或侧卧。有尿频、排尿不畅感,双小腿浮肿。否认有放射线及化学毒物接触史。体检:轻度贫血,腹膨隆,腹壁静脉曲张,肝未触及。脾大几乎占据全腹,表面光滑,质硬韧,无触痛。可扪脾切迹,甲乙线32.5cm,甲戍线43.5cm,丙丁线32cm,腹围93cm。实验室检查:Hb10g,RBC560万,WBC30,400(S77%,L6%),st11%,晚幼粒6%,网织红细胞1.5%,血小板4.8万,凝血酶原时间20秒,血
Primary myelofibrosis (AMM) underwent splenectomy treatment rare domestic reports, we have admitted a case reported as follows. Patient history Female, 47 years old. Abdominal mass gradually increased 17 years. Pelvic mass has been admitted to hospital, loss of appetite, weight loss and fatigue. Nearly half of bleeding gums, supine that sense of urgency, was forced to lie or lateral. Frequent urination, urinary incontinence, double calf edema. Denied the history of exposure to radiation and chemical poisons. Physical examination: mild anemia, abdominal bulging, abdominal varicose veins, liver not touched. Splenomegaly almost occupy the entire abdomen, the surface is smooth, hard and tough, no tenderness. May palpable splenic notch, A line B 32.5cm, Jiayu line 43.5cm, Ding Ding line 32cm, abdominal circumference 93cm. Laboratory tests: Hb10g, RBC5.6 million, WBC30,400 (S77%, L6%), st11%, late juvenile 6%, reticulocyte 1.5%, platelet 48000, prothrombin time 20 seconds, blood