在美国的莱姆病流行区,进行了21000多人的莱姆病疫苗接种的对照研究,证明伯氏疏螺旋体疫苗安全有效。莱姆病是通过蜱传播的自然疫源性疾病。最常见于美国。据美国疾病控制和预防中心报告,每年有10000个新病例。新近研究的疫苗由重组伯氏疏螺旋体和外脂膜蛋白A(OspA)组成,分2组,2次接种,间隔1个月,在12个月时加强1次。 A controlled study of Lyme disease vaccination in more than 21,000 people in Lyme disease endemic areas of the United States demonstrated that Borrelia burgdorferi vaccine is safe and effective. Lyme disease is a natural foci of disease transmitted by ticks. Most common in the United States. According to the U.S. Centers for Disease Control and Prevention, there are 10,000 new cases each year. The newly researched vaccine consisted of recombinant Borrelia burgdorferi and outer lipid membrane protein A (OspA) in two groups with two inoculations, one month apart and one fortified at 12 months.