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血清药物测定的合理使用指证是探查药物中毒。当药物使用的目的只为了预防时,药物测定亦可能是必须的。药物测定在评价种种药剂的吸收、代谢和药物作用上起有重要作用。狄戈辛测定在洋地黄中毒中的作用在心脏病患者中,洋地黄中毒是一主要的临床问题,1971年 Beller 等报告住院用洋地黄的病人中有23%被证实为肯定有药物中毒,另6%为可能药物中毒。药物中毒病人的死亡率是无药物中毒病人的两倍。目前,由于广泛使用洋地黄测定,洋地黄中毒已不普遍。复习最近文献40篇,发现无药物中毒病人的平均血清狄戈辛浓度小于2ng/ml;而临床证实中毒的病人其平均血清浓度在2ng/ml
Proper use of serum drug testing is evidence of drug poisoning. Drug testing may also be necessary when the purpose of drug use is only for prevention. Drug assays play an important role in assessing the absorption, metabolism and drug action of various agents. Digitalis determination of the role of digitalis poisoning Heart disease, digitalis poisoning is a major clinical problem in 1971, Beller and other reports of digitalis inpatients, 23% of patients confirmed as surely drug poisoning, Another 6% is possible drug poisoning. Drug-poisoning patients have twice as many fatalities as drug-free patients. At present, digitalis poisoning is not widespread due to the widespread use of digitalis assay. Review of the recent literature 40, found no drug poisoning patients with the average serum concentration of Dioxin less than 2ng / ml; and clinical confirmed poisoning patients with an average serum concentration of 2ng / ml