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本文对采用顺铂与放疗并用治疗的23例中晚期食管癌进行了临床资料分析。完全缓解5例,部分缓解11例,总缓解率(CR+PR)为69.5%。有效16例,中数缓解期7.1月,明显优于联合化疗(PIM、VCR、DDP)缓解期2.5月。毒性反应主要是恶心、呕吐,病人均能耐受。该方案能延长中晚期食管癌病人的缓解期,改善生存质量,值得推广使用。临床所见食管癌患者多为中晚期,已失去手术治疗机会。平阳霉素(PIM)、长春新碱(VCR)和顺铂(DDP)三药联合化疗是目前治疗食管癌较好的方案之一,但缓解期短
In this paper, the clinical data of 23 patients with advanced esophageal cancer treated with cisplatin and radiotherapy were analyzed. Complete remission in 5 cases, partial remission in 11 cases, total remission rate (CR+PR) was 69.5%. Effective in 16 cases, the median remission period of 7.1 months, significantly better than the combined chemotherapy (PIM, VCR, DDP) remission period of 2.5 months. The main toxicities were nausea and vomiting, and all patients were tolerant. The program can prolong the remission period of patients with advanced esophageal cancer, improve the quality of life, it is worth promoting. Most of the esophageal cancer patients seen in the clinic are in advanced stages and have lost surgical treatment. The combination of pingyangmycin (PIM), vincristine (VCR) and cisplatin (DDP) is one of the better treatments for esophageal cancer, but the remission period is short.