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观察了８０例特发性血小板减小性紫癜（ＩＴＰ），治疗前血小板数均值为１９×１０９／Ｌ并伴有明显出血症状。选择口服醋酸泼尼松组１９例，剂量为１ｍｇ／ｋｇ，疗程６—８周。静脉丙种球蛋白组２８例，剂量为０．２５—０．４０／ｋｇ，时间为２—５天，用前给地塞米松３—５ｍｇ预防过敏反应。免疫抑制组１１例为西艾克３ｍｇ／ｍ２／周或ＶＣＲ１．５ｍｇ／ｍ２／周，静脉缓慢滴注，用４—６次。切牌组１９例均选择激素无效或依赖者。醋酸泼尼松组显效率为５７．９％，无效率为１０．５％，总有效率为８９．５％。静脉丙种球蛋白组２８例，完全反应率为７１．４％，总有效率为８９．３％。切脾组显效率为８４％，总有效率为８９．５％。长春新碱总有效率为６３．６％。醋酸泼尼松仍作为首选药物。静脉丙种球蛋白费用昂贵，只能作为急救药物，适于急重症ＩＴＰ，采用小剂量静脉丙种球蛋白仍可获得满意的疗效，并可减少病人负担。切脾应掌握适应症，选择年龄大于４岁和病程半年以上为宜，因年龄太小易出现凶险感染。长春新碱类药物适于难治性ＩＴＰ或年幼儿不能切脾的重症ＩＴＰ。
80 cases of idiopathic thrombocytopenic purpura (ITP) were observed. The average number of platelets before treatment was 19 × 109 / L with obvious bleeding symptoms. In the oral prednisone group, 19 patients were selected at a dosage of 1 mg / kg for 6-8 weeks. Intravenous gamma globulin in 28 cases, a dose of 0.25-0.40 / kg, the time is 2-5 days, before dexamethasone 3-5mg to prevent allergic reactions. Eleven patients in the immunosuppressive group were treated with Sialyl 3 mg / m 2 / week or VCR 1.5 mg / m 2 / week with a slow intravenous drip 4-6 times. Twenty-nine patients in the treated group were all inactive or dependent. In prednisone acetate group, the effective rate was 57.9%, the inefficiency rate was 10.5% and the total effective rate was 89.5%. 28 cases of intravenous gamma globulin, the complete response rate was 71.4%, the total effective rate was 89.3%. The effective rate of splenectomy group was 84%, the total effective rate was 89.5%. The total effective rate of vincristine was 63.6%. Prednisone acetate is still the drug of choice. Intravenous gamma globulin is expensive and can only be used as a rescue medication for acute ITP. A small dose of intravenous gamma globulin can still be used to achieve satisfactory efficacy and reduce patient burden. Spleen should be indications, choose age greater than 4 years of age and duration of more than six months is appropriate, due to age is too small prone to dangerous infection. Vincristine is suitable for refractory ITP or severe ITP in young children who can not spleen.