建立了毛细管气相色谱法测定酒石酸托特罗定中的8种有机溶剂——甲醇、乙醇、乙腈、二氯甲烷、乙酸乙酯、四氢呋喃、吡啶和甲苯的残留量。以DMSO为溶剂,正丙醇为内标,采用程序升温。各溶剂的平均回收率分别为99.4%、101.1%、100.6%、100.3%、100.9%、101.0%、99.6%和101.2%,RSD小于1.0%。 A capillary gas chromatography was developed for the determination of the residues of the eight organic solvents - methanol, ethanol, acetonitrile, methylene chloride, ethyl acetate, tetrahydrofuran, pyridine and toluene in the tocotrint tartrate. With DMSO as solvent, n-propanol as internal standard, the program temperature. The average recoveries for each solvent were 99.4%, 101.1%, 100.6%, 100.3%, 100.9%, 101.0%, 99.6% and 101.2%, respectively, with a RSD of less than 1.0%.