目的:来曲唑联合人绝经期促性腺激素的夫精人工授精(AIH)临床治疗效果.方法:分析2017年12月至2021年8月于本中心医院完成随访的363个AIH周期,根据患者促排卵方式分组,分为来曲唑(LE)组、来曲唑联合人绝经期促性腺激素(HMG)组和自然周期组,探讨来曲唑联合人绝经期促性腺激素的夫精人工授精(AIH)临床治疗效果.结果:LE组、LE+HMG组和自然周期的女方年龄分别为29.10±3.38岁、27.58±3.83岁、29.62±4.06岁;优势卵泡数分别为1.27±0.55个、1.38±0.72个“,”Objective: The clinical therapeutic effect of letrozole combined with human menopausal gonadotropin on AIH. Methods Analyzed 363 AIH cycles that were followed up in our central hospital from December 2017 to August 2021. The patients were grouped according to the ovulation induction method and divided into letrozole (LE) group, letrozole combined with human menopausal gonadotropin (HMG) group and natural cycle group, to explore the clinical therapeutic effect of letrozole combined with human menopausal gonadotropin on AIH. Results The ages of the women in the LE group, LE+HMG group and natural cycle were 29.10±3.38 years old, 27.58±3.83 years old, 29.62±4.06 years old; the number of dominant follicles were 1.27±0.55, 1.38±0.72, 1.11±0.47, respectively , The difference was statistically significant (P＜0.05); the clinical pregnancy rates among LE group, LE+HMG group and natural cycle group were 10.43％, 20.00％, 4.55％, respectively; live birth rates were 8.26％, 15.56％, 2.27％; and there were no significant differences in the number of years of infertility, BMI treatment cycles, endometrial thickness, fetal weight, and abortion rate between the three groups (P＞0.05). Conclusion In artificial insemination of husband\'\'s sperm, letrozole combined with human menopausal gonadotropin can provide patients with a good therapeutic effect and pregnancy outcome.