Melkersson－Rosenthal综合征（简称MRS）是以周围性面瘫、反复唇（面）水肿、皱努舌为特征的少见综合征，而伴多颅神经损害则罕见。现将本科1例，报告如下。患者男性，27岁，于1996年5月入院。5年前右面部肿胀，2个月后波及对侧面部及上下唇，双眼睑闭合不能，服强的松后水肿 Melkersson-Rosenthal syndrome (referred to as MRS) is a rare syndrome characterized by peripheral facial paralysis, repeated lip (surface) edema, wrinkles and annuluses, but with multiple cranial nerve damage is rare. Now undergraduate 1 cases, the report is as follows. The patient, male, 27 years old, was admitted to hospital in May 1996. 5 years ago, the right facial swelling, 2 months after the spread to the lateral and upper and lower lip, double eyelid closure can not, with strong edema