前列腺素类药物是一类属于20个碳的不饱和脂肪酸化合物。60年代中期提纯了前列腺素E(PGE)、前列腺素D(PGD)、前列腺素F(PGF)等前列腺素系列药物。70年代中期,发现血小板和血管壁可分别合成和释放两种作用相反的前列腺素类物质——血栓烷A_2(TXA_2)和前列腺环素(PGI_2),这两种物质的发现使前列腺素研究在生化、生理和药理等方 Prostaglandins are a class of unsaturated fatty acid compounds belonging to 20 carbons. In the mid 60’s, prostaglandin E (PGE), prostaglandin D (PGD), prostaglandin F (PGF) and other prostaglandin drugs were purified. In the mid-1970s, it was found that platelets and blood vessel walls can synthesize and release two prostaglandins, TXA_2 and PGI_2, respectively, which have the opposite effects. The discovery of these two substances makes prostaglandin studies in Biochemical, physiological and pharmacological and other parties