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目的：观察果糖二磷酸钠（ＦＤＰ）治疗脑梗死伴冠心病的疗效。方法：脑梗死伴冠心病４０例（男性２３例，女性１７例，年龄５９±ｓ１２ａ），在常规药物（胞磷胆碱、曲克芦丁等）治疗的同时，治疗组给予ＦＤＰ５ｇ，溶于注射用水５０ｍＬ中ｉｖ，ｄｒｉｐ，ｑｄ×１０ｄ；对照组４０例病人（男性２４例，女性１６例，年龄６０±１３ａ）则给予复方丹参２０ｍＬ加入６％低分子羟乙基淀粉３００ｍＬ中，ｉｖ，ｄｒｉｐ，ｑｄ×１０ｄ。结果：脑梗死和冠心病的总有效率ＦＤＰ组分别是９２％和１００％，复方丹参组是７５％和８５％，２组比较Ｐ＜０．０５。２组副作用均轻微。结论：ＦＤＰ是治疗脑梗死伴冠心病的有效药物。
Objective: To observe the effect of fructose diphosphate (FDP) on cerebral infarction with coronary heart disease. Methods: Cerebral infarction with coronary heart disease in 40 cases (23 males and 17 females, age 59 ± s12a), in the conventional drugs (citicoline, troxerutin, etc.) treatment, the treatment group given FDP5g, dissolved in Drip, qd × 10d; control group of 40 patients (24 males and 16 females, age 60 ± 13a) were given 20mL salvia miltiorrhiza Blend 6% low molecular weight hydroxyethyl starch 300mL, iv, drip, qd × 10d. Results: The total effective rate of cerebral infarction and coronary heart disease were 92% and 100% in the FDP group, 75% and 85% in the compound Salvia miltiorrhiza group, and both groups had slight side effects when compared with the P <0.05.2 group. Conclusion: FDP is an effective drug for treating cerebral infarction with coronary heart disease.