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目的:探讨邮票皮、Meek皮在大面积烧伤患者创面修复中治疗效果差异。方法:选取2016年3月至2018年2月陆军第七三集团军医院诊治大面积烧伤患者81例进行研究，根据患者术前选择创面修复方式分为A组(邮票皮植皮，35例)和B组(Meek皮植皮，46例)，比较两组患者皮片存活和愈合情况、治疗费用、死亡情况及康复情况。结果:A组和B组患者植皮皮片一期存活率及创面愈合率、患者死亡率比较差异无统计学意义(82.86% vs 86.96%，5.71% vs 8.70%，n P>0.05)。A组患者皮片成活率高于B组，创面愈合时间、1%体表总面积(TBSA)烧伤面积治疗费用均低于B组[(76.3±5.1)% vs (67.9±6.2)%，(41.5±4.9)d vs (45.8±5.1)d，(1 215.6±235.1)元vs (7 689.5±681.0)元，n P<0.05]。A组患者康复优良率显著低于B组(68.57% vs 86.96%，n P0.05). The survival rate of skin graft in group A was higher than that in group B, and the wound healing time and treatment cost of 1% total body surface area (TBSA) in group A were lower than those in group B [(76.3±5.1)% vs (67.9±6.2)%, (41.5±4.9)d vs (45.8±5.1)d, (1 215.6±235.1)yuan vs (7 689.5±681.0)yuan,n P<0.05]. The excellent and good rate of rehabilitation in group A was significantly lower than that in group B (68.57% vs 86.96%,n P<0.05).n Conclusions:The application of the stamp skin in the repair of wounds in large-area burn patients has a higher flap survival rate than meek skin repair, which can shorten the healing time of the flap and reduce the treatment cost, but the rehabilitation effect is poor.