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检查慢性实质性腮腺炎25例,Sj?gren氏病31例,用花环形成试验测定外周血T和B淋巴细胞数;加PHA培养进行淋巴细胞转化试验,检查T细胞对PHA刺激的应答能力;进行补体结合试验,根据淋巴细胞致敏和抗涎腺抗体水平评定自身免疫反应;测定血清IgG,IgA,IgM和循环的免疫复合物(CIC)含量.对照组为30例健康人.检查结果慢性实质性腮腺炎患者,血淋巴细胞相对数(百分数)增高(P<0.05),T细胞绝对数增多(p<0.05),B细胞增多,血清IgA含量增高(p<0.05),T细胞对PHA刺激的应答能力下降,血清
25 cases of chronic mumps and 31 cases of Sjögren’s disease were examined. The numbers of T and B lymphocytes in peripheral blood were measured by means of rosette formation test. Lymphocyte transformation test was performed in PHA culture to examine the ability of T cells to respond to PHA stimulation. The complement fixation test was carried out and the autoimmune response was evaluated according to lymphocyte sensitization and anti-salivary gland antibody level. The levels of serum IgG, IgA, IgM and circulating immune complex (CIC) were measured, and the control group was 30 healthy people. In mumps, the relative numbers of blood lymphocytes increased (P <0.05), the absolute number of T cells increased (P <0.05), the number of B cells increased and the content of serum IgA increased (p <0.05) The ability to respond decreased, serum