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目的 :探讨癫儿童发作前期脑电变化的复杂性。方法 :应用非线性分析方法对 2 3例癫儿童的 83次发作 (39次全身性发作 ,44次部分性发作 )进行发作前脑电复杂度分析。结果 :发作间期基础脑电平均复杂度在清醒期、NREM睡眠Ⅱ期和Ⅲ期分别为 0 33,0 2 4,0 16。清醒期自发作前 2 1min ,NREM睡眠Ⅱ期从发作前 10min开始 ,脑电复杂度显著降低。复杂度变化与发作类型无关。结论 :癫发作前脑电复杂度长时间在低水平徘徊 ,它可能是神经元活动同步化程度增高的反应。复杂度变化的程度与发作所处的状态有关 ,基础状态复杂度越高 ,发作前的降低越明显。发作前复杂度的变化可能主要与不同的发作机制而不是与临床发作类型有关。
Objective: To explore the complexity of EEG changes in children with epileptic seizures. METHODS: Non-linear analysis was used to analyze the EEG complexity of 83 episodes (39 episodes of generalized episodes, 44 partial episodes) in 23 epileptic children. Results: The average complexity of the basal electroencephalogram (EEG) in interictal seizures was at awake stage. The NREM sleep stages Ⅱ and Ⅲ were 0 33,0 2 4,0 16 respectively. In the awake period, spontaneous onset before 21min, NREM sleep stage Ⅱ 10min before onset, EEG complexity was significantly reduced. Complexity changes have nothing to do with the type of attack. Conclusion: The complexity of electroencephalogram before epileptic seizures hovers at a low level for a long time, which may be the response to the increase of synchronization of neuronal activity. The degree of complexity changes with the state of the attack, the higher the complexity of the basic state, the more obvious the pre-seizure decrease. The complexity of pre-seizure changes may be mainly related to different seizure mechanisms rather than the type of clinical seizure.