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目的:观察中药内服及外敷联合前列腺按摩治疗慢性非细菌性前列腺炎(CNP)的疗效。方法:将200例CNP患者随机分为2组各100例,治疗组予内服前乐舒汤、外敷前乐宁散配合前列腺按摩治疗;对照组予口服前列解毒胶囊联合前列腺按摩治疗,2组均治疗30天。治疗前、后分别对2组患者前列腺炎症状问卷(NIH-CPS)I症状评分、前列腺液中白细胞、红细胞、脓细胞、卵磷脂小体数量进行记录和比较。结果:临床治愈率、总有效率治疗组分别为35%、92%,对照组分别为13%、79%,2组比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。治疗后2组疼痛或不适感、排尿异常、生活质量影响积分及总分均较治疗前明显下降,卵磷脂小体升高,差异均有非常显著性意义(P<0.01);治疗组各项积分下降较对照组更为显著(P<0.05,P<0.01)。治疗后治疗组前列腺液中白细胞、脓细胞均较治疗前明显下降(P<0.01);治疗后治疗组前列腺液中白细胞、脓细胞均较对照组下降(P<0.05),卵磷脂小体较对照组升高(P<0.05)。结论:内服前乐舒汤、外敷前乐宁散配合前列腺按摩治疗CNP临床疗效确切。
Objective: To observe the curative effect of traditional Chinese medicine (TCM) and external application combined with prostate massage in the treatment of chronic nonbacterial prostatitis (CNP). Methods: 200 cases of CNP were randomly divided into two groups of 100 cases. The treatment group was treated with Qianleshutang before external application of Lonning powder and prostate massage. The control group was given oral Qianliejiedu capsule combined with prostate massage. Treatment for 30 days. Before and after treatment, the symptom score of NIH-CPS I and the number of leukocyte, erythrocyte, pus and lecithin in prostatic fluid were recorded and compared respectively. Results: The clinical cure rate and total effective rate were 35% and 92% respectively in the treatment group and 13% and 79% in the control group respectively. There was significant or very significant difference between the two groups (P <0.05, P <0.01) ). After treatment, pain or discomfort, voiding dysfunction, quality of life scores and total scores of two groups were significantly lower than those before treatment and lecithin was increased, both of which had significant difference (P <0.01) The integral decline was more significant than the control group (P <0.05, P <0.01). After treatment, the number of leukocytes and pus in prostatic fluid in treatment group decreased significantly compared with those before treatment (P <0.01). After treatment, the number of leukocytes and pus in prostatic fluid in treatment group decreased compared with that in control group (P <0.05) The control group increased (P <0.05). Conclusion: Before oral administration of Lok Shu Tang, external topical Lining Ning with prostate massage for the treatment of CNP exact effect.