Suppressive effect of intestinal extract from stressed rats on lymphocyte proliferation

来源 :Acta Pharmacologica Sinica | 被引量 : 0次 | 上传用户:xhb74
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Our previous work showed that an immune suppressive protein, with a molecular weight of 155 and 370 kDa, was generated in spleen and lymph node in rats treated with stress. The protein strongly inhibited lymphocyte proliferation in vitro. In the present study the extract of intestine from the rats treated with restraint stress was also suppressive on lymphocyte proliferation.The further experiments showed that the bio-activity and molecular weight of the extract were all similar to the Our previous work showed that an immune suppressive protein, with a molecular weight of 155 and 370 kDa, was generated in spleen and lymph node in rats treated with stress. The protein strongly demonstrated lymphocyte proliferation in vitro. In the present study the extract of intestine from the rats treated with restraint stress was also suppressive on lymphocyte proliferation.The further experiments showed that the bio-activity and molecular weight of the extract were all similar to the
其他文献
关于酸枣仁的传说在我国,酸枣仁入药尤早,其气微弱,味甘性平无毒,《神农本草经》列其为上品。其为鼠李科植物酸枣的种子,主产河北、陕西、辽宁、河南等省,以粒大饱满,肥厚油
“辛、甘而温,气薄升浮。入太阴肺、太阳膀胱经。温经通脉,发汗解肌。治伤风头痛,中风自汗,调和营卫,使邪从汗出,而汗自止。亦治手足痛风、胁风。”此《本草备要》之述桂枝,
There is a bidirectional flow of information between immune and central nervous systems.Interferon-α(IFN-α) is not only an important immunoregulatory factor,
GeneticanalysisofNacetyltransferasepolymorphisminaChinesepopulation1LUJianFeng2,CAOXiaoMei,LIUZhiHai3,CAOWen,GUOLianQing... GeneticanalysisofN  acetyltransferasepolymorphisminaChinesepopulation1LUJianFeng2, CAOXiaoMei, LIUZhiHai3, CAOWen, GUOLia
热激活蛋白(热休克蛋白,HSP)为一组具有保守结构的蛋白,细胞在亚致死性热休克及各种应激因子的作用下可诱导或加速其合成。HSP可能与风湿热(RF)的风湿性关节炎(RA)的致病机
大家都知道西药有过敏,认为中药不会过敏,其实这种认识是错误的。中药过敏往往与用法、用量关系不大,而与个人体质,如用药者的遗传基因、体内代谢酶及免疫系统等有关。近年来
最近,国内专家组对近两个月来全国379例明确诊断的甲型流感病例进行了疗效分析。结果表明,中医药防治甲型H1N1型流感是一种安全有效的方法。在疗效上,中药与达菲等抗流感西药
法学期刊对推动中国近20余年社会整体法治水平的发展发挥了不可或缺的作用,围绕这一话题,本刊特别组织了一组文章进行讨论。文章表明,法学期刊在繁荣法学理论、促进国家法治
一个品牌最持久的含义是它的价值、文化和个性,它们构成了品牌的基础,因而出版经营工作要注意时刻围绕其出版价值、出版文化和出版个性来开展工作。一般说来,品牌经营包括品牌定
Opc蛋白是脑膜炎奈瑟菌(Nm)的主要毒力因子之一,它可介导该菌吸附和侵入宿主表皮和内皮细胞,并对人体具有高度免疫原性。近年来各国学者对该蛋白的分子生物学、免疫学和致病