新加坡1958年开始在儿童中大量服食 SabinⅡ型减毒脊灰炎病毒疫苗,并于1962年3月采用全国儿童抗脊灰炎免疫计划,每年有超过85％的婴儿和95％以上的小学入学新生接受免疫,导致这个国家清除了麻痹型脊灰炎。1976年曾对1955年～1958年出生而未进行抗脊灰炎免疫接种的人群进行血清免疫研究,结果显示他们中35. 4％仍对脊灰灸病毒易感。这一发现引起人们很大的关注,因为未能肯定 Singapore started taking large doses of Sabin II attenuated poliovirus vaccine among children in 1958 and adopted the national anti-polio immunization program for children in March 1962. Each year more than 85% of infants and 95% of primary schools enroll in schools The newborn receives immunity, causing the country to clear paralytic poliosis. Serum immunization studies of people born in 1955 to 1958 but not immunized against poliomyelitis in 1976 showed that 35.4% of them were still susceptible to poliovirus. This discovery aroused great concern because it was not confirmed