中药十八反作为中药药性理论的重要组成部分,古往今来,一直被视为临床医家配伍用药的“禁区”。为了避免造成麻烦,多数医家不愿轻举妄用。然而,成功地运用十八反的例证也代有所传。这就给后世留下了千古不解之迷。诸如中药相反的本意和本质是什么,十八反药物究竟相反还是不反,现今临床应如何对待十八反等等,都是亟待揭示的问题。近二十余年来,先后发表的四十余篇文章从不同角度探讨了这些问题,取得了一些进展。但是,由于研究的方法特别是思路方法不同,所得结论亦 As an important part of the traditional Chinese medicine theory, traditional Chinese medicine has been regarded as the “forbidden zone” for the compatibility of clinical doctors. In order to avoid causing trouble, most doctors are reluctant to use it lightly. However, the successful use of the example of the eighteen antithesis also passed on. This left the fans behind the ages. What is the opposite of the original intention and essence of traditional Chinese medicine, such as the eighteen anti-drugs, the opposite is still not the opposite, and how clinical treatment should be treated today is an issue that needs to be revealed. Over the past two decades, more than forty articles published successively have explored these issues from different perspectives and made some progress. However, due to differences in research methods, especially ideas and methods, the conclusions are also