论文部分内容阅读
目的探讨新疆乌鲁木齐市维吾尔族人群成人支气管哮喘的影响因素。方法本研究采用成组匹配病例对照研究方法,病例组为新疆医科大学第一附属医院呼吸内科在2014年1-12月确诊的维吾尔族支气管哮喘成人患者(n=120例),对照组为同期体检中心健康维吾尔族体检者(n=126例),两组在年龄、性别相匹配。采用问卷调查的方法收集相关暴露资料,并采用单因素分析及多因素非条件Logistic回归模型分析成人支气管哮喘影响因素。结果多因素Logistic回归分析显示,吸烟(OR=1.88,95%CI:1.28~2.96)、家族支气管哮喘史(OR=6.20,95%CI:2.10~18.31)、家中铺有纯毛地毯数量多(OR=1.87,95%CI:1.18~2.95),睡眠质量(OR=1.46,95%CI:1.22~1.75),患慢性支气管炎(OR=13.43,95%CI:6.65~25.34)及过敏性鼻炎(OR=6.27,95%CI:3.63~10.81)是维吾尔族成人支气管哮喘的主要影响因素。结论维吾尔族成人支气管哮喘是生活方式、环境及遗传等多种因素共同作用的结果,应加强对相关影响因素的预防及治疗,减少哮喘的发生,改善哮喘患者生活质量。
Objective To investigate the influencing factors of adult bronchial asthma in Uighur population in Urumqi, Xinjiang. Methods In this study, a group matched case-control study was conducted. The case group was an adult Uygur bronchial asthma patient (n = 120) diagnosed in Department of Respiratory Medicine, First Affiliated Hospital of Xinjiang Medical University from January to December 2014. The control group Health Uygur physical examination center (n = 126 cases), the two groups in age and gender match. The related exposure data were collected by questionnaire survey, and the influencing factors of adult bronchial asthma were analyzed by univariate analysis and multivariate non-conditional Logistic regression model. Results The multivariate Logistic regression analysis showed that there was a significant increase in smoking (OR = 1.88,95% CI: 1.28-2.96), family history of bronchial asthma (OR = 6.20,95% CI: 2.10-18.31) OR = 1.87, 95% CI: 1.18-2.95), sleep quality (OR = 1.46, 95% CI: 1.22-1.75), chronic bronchitis (OR = 13.43, 95% CI: 6.65-25.34) and allergic rhinitis (OR = 6.27, 95% CI: 3.63-10.81) are the main influencing factors of Uygur adults with bronchial asthma. Conclusions Adult Uygur bronchial asthma is the common result of many factors such as lifestyle, environment and genetics. Prevention and treatment of related factors should be strengthened to reduce the incidence of asthma and improve the quality of life of asthma patients.