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在精子获能过程中,有环磷酸腺苷(cAMP)参与。磷酸二脂酶抑制剂或cAMP类似物加速小鼠精子获能。由于人精子内cAMP浓度与受精能力或细胞内游离钙浓度无明显相关,cAMP对人精子获能的重要性仍存争议。
During sperm capacitation, cyclic adenosine monophosphate (cAMP) is involved. Phosphodiesterase inhibitors or cAMP analogs accelerate mouse sperm capacitation. The importance of cAMP on human sperm capacitation remains controversial as there is no significant correlation between cAMP concentration in human sperm and fertilization or intracellular free calcium concentration.