论文部分内容阅读
土贝母皂甙Aip2mg／kg对小鼠脾脏空斑形成细胞显著增高（P＜0．01），而po50mg／kg使小鼠脾脏空斑形成细胞下降（P＜0．01），po同剂量可使胸腺重量显著减轻（P＜0．01），使血清补体C3含量显著增高（P＜0．01），土贝母皂甙A和土贝母皂甙B对大鼠实验性变态反应性脊髓炎、特异性超敏反应有抑制作用。无论ip或po对小鼠血清溶血素生成、IgG含量及总补体活性均无明显影响。
The amount of plaque-forming cells in the spleen of mice was significantly increased (P<0.01), while the plaque formation cells in the spleen of mice were decreased by po50mg/kg (P<0.01). The weight of the thymus was significantly reduced (P<0.01), the serum complement C3 content was significantly increased (P<0.01), and the Fritillaria saponins A and Fritillaria saponins B were used to treat experimental allergic myelitis in rats. Specific hypersensitivity has an inhibitory effect. Both ip and po had no significant effect on mouse serum hemolysin production, IgG content and total complement activity.