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目的分析心肌肌钙蛋白T(cTnT)、肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白I(cTnI)指标变化与急性心肌梗死范围相关性。方法研究对象来自本院心内科2011年2月~2013年5月收治的100例急性心肌梗死患者,测定急性心肌梗死患者cTnT、CK-MB和cTnI水平。采用Pearson分析cTnT、CK-MB和cTnI水平与急性心肌梗死梗死范围的相关性。结果治疗7 d后,患者cTnT、CK-MB和cTnI均显著下降,差异有统计学意义P<0.05。急性心肌梗死患者cTnT、CK-MB和cTnI与梗死范围呈正相关,相关系数r分别为0.992、0.932和0.987,差异有统计学意义P<0.05,且急性心肌梗死患者不同梗死范围患者cTnT、CK-MB和cTnI指标存在明显界限。结论 cTnT、CK-MB和cTnI水平在急性心肌梗死患者中明显升高,指标升高程度与急性心肌梗死范围有着密切关系。
Objective To analyze the correlation between cardiac troponin T (cTnT), creatine kinase isoenzyme (CK-MB) and cardiac troponin I (cTnI) and the range of acute myocardial infarction. Methods The subjects were from 100 patients with acute myocardial infarction admitted from February 2011 to May 2013 in our hospital. The levels of cTnT, CK-MB and cTnI in patients with acute myocardial infarction were measured. Pearson analysis of cTnT, CK-MB and cTnI levels and acute myocardial infarction range of relevance. Results After 7 days of treatment, the cTnT, CK-MB and cTnI in patients were significantly decreased, the difference was statistically significant (P <0.05). The correlation coefficients of cTnT, CK-MB and cTnI in patients with acute myocardial infarction were positively correlated with the infarct size, the correlation coefficients r were 0.992,0.932 and 0.987 respectively, with statistical significance (P <0.05). In patients with acute myocardial infarction, cTnT, CK- MB and cTnI indicators have obvious boundaries. Conclusion The levels of cTnT, CK-MB and cTnI in patients with acute myocardial infarction were significantly higher than those in patients with acute myocardial infarction.