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近两年来,我院药学系中草药化学教研室和基础医学系药理教研室协作,在灵芝多糖的研究方面取得了初步成果。从灵芝[赤芝,Ganoderma lucidum(Leyss ex Fr.)Karst]子实体中提取出数种多糖,经初步药理实验证明;灵芝多糖具有镇静作用、强心作用和提高实验动物耐受常压缺氧的能力,是灵芝的重要有效成分之一。 对主要含小分子多糖和氨基酸的灵芝多糖部分进行的深入药理研究表明,此部分多糖能使小鼠腹腔巨噬细胞吞噬鸡红血球的能力显著增加,吞噬百分率和吞噬指数分别增加26.3％和
In the past two years, the Department of Pharmacology of Chinese Herbal Medicine in our hospital has cooperated with the Department of Pharmacology of the Department of Pharmacology of Basic Medicine, and achieved preliminary results in the research of Ganoderma lucidum polysaccharides. Several polysaccharides were extracted from the fruiting body of Ganoderma lucidum (Leyss ex Fr.) Karst, and preliminary pharmacological experiments showed that the polysaccharides of Ganoderma lucidum have sedative effect, cardiac stimulant effect, and increased resistance to atmospheric hypoxia in experimental animals. Ability is one of the important active ingredients of Ganoderma lucidum. The in-depth pharmacological studies on the polysaccharides of ganoderma lucidum, which mainly contain small-molecule polysaccharides and amino acids, show that this part of the polysaccharide can significantly increase the ability of mouse peritoneal macrophages to phagocytose chicken erythrocytes, and the percentages of phagocytosis and phagocytosis increase by 26.3% and