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比较了脊髓灰质炎（脊灰）糖丸疫苗和液体疫苗基础免疫的血清学效果。观察对象为近５年无脊灰流行的农村．共１０２名２～６月龄未服过脊灰疫苗的婴儿，按月龄和性别均衡地分为糖丸疫苗组和液体疫苗组。两组都有部份婴儿有母传抗体，服苗前各型脊灰中和抗体的阳性率为１１．７６％～１９．１５％。几何平均滴度（ＧＭＴ）１：１．１８～１：２．４５。全程３次服苗后，抗体阳转率和４倍增长率均达到１００％，两组之间差异无显著的统计学意义；ＧＭＴ亦达到１：７８．７６～１：１１５．３６，两组之间也无显著性差异。这表明两种剂型的脊灰疫苗均有良好的免疫效果。液体疫苗因服用方便，更适合于０～８月龄婴儿。
The serological effects of poliomyelitis (poliomyelitis) sugar pill vaccine and liquid vaccine based immunity were compared. Observed for the past 5 years, polio-free rural areas. A total of 102 infants aged 2 ~ 6 months who did not receive polio vaccine were evenly divided into sugar pill group and liquid vaccine group according to age and gender. In both groups, some infants had maternal antibodies. The positive rates of neutralizing antibodies against various types of poliovirus before serving in each group ranged from 11.76% to 19.15%. Geometric mean titer (GMT) 1: 1.18 ~ 1: 2.45. After three doses of whole-dressing vaccine, the rate of antibody positive rate and the rate of 4-fold increase reached 100% respectively, with no significant difference between the two groups; the GMT reached 1: 78.76 ~ 1: 115.36, There is no significant difference between. This shows that both formulations of polio vaccine have a good immune effect. Liquid vaccine for taking convenience, more suitable for 0 to 8 months old infants.