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目的:探讨肝炎肝硬变腹水并发原发性腹膜炎应用第3代头孢菌素类药物的治疗效果。方法:31例肝炎肝硬变腹水并发原发性腹膜炎患者应用头孢三嗪或头孢氨噻肟静脉滴注治疗。疗程10～14d。结果:治愈20例 (64.5％),死亡11例(35.5％),其中死于感染性休克3例,上消化道出血1例,肝性脑病5例,肝肾综合征2例。结论:第3代头孢菌素类药物——头孢三嗪和头孢氨噻肟是治疗肝炎肝硬变腹水并发原发性腹膜炎的理想药物。
Objective: To investigate the treatment of hepatitis C cirrhosis with primary peritonitis using third-generation cephalosporins. Methods: Thirty-one patients with hepatitis cirrhosis with primary peritonitis were treated with intravenous infusion of ceftriaxone or cefotaxime. Treatment 10 ~ 14d. Results: Twenty patients (64.5%) were cured and 11 died (35.5%), of which 3 died of septic shock, 1 had upper gastrointestinal bleeding, 5 had hepatic encephalopathy and 2 had hepatorenal syndrome. Conclusion: The third generation cephalosporins - ceftriaxone and cefotaxime is the ideal drug for the treatment of hepatitis with cirrhosis ascites complicated by primary peritonitis.