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目的探讨胃粘膜相关淋巴组织(MALT)淋巴瘤与幽门螺杆菌(Hp)感染的相关性。方法经手术和病理确诊的原发性胃恶性淋巴瘤患者17例,行常规病理和免疫组化染色,重新作出病理学诊断,并观察Hp感染情况。结果确诊胃MALT淋巴瘤14例,其中12例Hp阳性。14例中术前误诊7例,误诊为慢性胃炎3例,良性胃溃疡2例,胃癌2例。结论胃MALT淋巴瘤与Hp感染密切相关,术前误诊率高。
Objective To investigate the correlation between gastric mucosa-associated lymphoid tissue (MALT) lymphoma and Helicobacter pylori (Hp) infection. Methods Twenty-seven patients with primary gastric malignant lymphoma confirmed by operation and pathology were routinely pathologically and immunohistochemically stained for pathological diagnosis and Hp infection was observed. Results Gastric MALT lymphoma was diagnosed in 14 cases, of which 12 were Hp positive. Of the 14 cases, 7 were misdiagnosed preoperatively, 3 were misdiagnosed as chronic gastritis, 2 were benign gastric ulcer and 2 were gastric cancer. Conclusion Gastric MALT lymphoma is closely related to Hp infection, with a high preoperative misdiagnosis rate.