人脂肪干细胞(h SCs)是一种丰富、易得的多能成体干细胞[1]。尽管我们可获取大量吸脂术后的脂肪,但是细胞治疗所需的大量未分化存活细胞仍需要通过高效的体外扩增方法才能得到。例如,在一项旨在改善肌肉萎缩症,并以小鼠为模型的治疗实验中,我们在每月一次注射106个细胞时得到了阳性结果[2]。如果我们将其应用于人体,一个体重60 kg的人每月大约需要3×109个干细胞。我们试验 Human adipose-derived stem cells (hSCs) are abundant and readily available pluripotent adult stem cells [1]. Although we can obtain a large amount of fat after liposuction, a large number of undifferentiated viable cells required for cell therapy still need to be obtained by an efficient in vitro amplification method. For example, in a treatment experiment designed to ameliorate muscular dystrophy and mouse-based models, we obtained positive results at a monthly injection of 106 cells [2]. If we apply it to the human body, a person weighing 60 kg will need about 3 x 109 stem cells per month. We test