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为探究告达亭(Caudatin)对雄性昆明小鼠的毒性影响,按照告达亭质量比为5和10 mg/kg以及溶剂对照组对SPF级昆明鼠通过腹腔注射的方法,进行为期14 d的毒理学研究.实验动物总共30只昆明鼠,随机分为6组,分2批进行实验,两次实验结果一致:实验昆明鼠在不同浓度告达亭处理14 d后体质量无明显变化,血液学指标检测正常,心、肝、肺、肾以及睾丸均无组织畸变.
In order to explore the toxic effects of Caudatin on male Kunming mice, mice were sacrificed at the dose of 5 and 10 mg / kg, and the SPF Kunming mice were injected intraperitoneally with solvent group for 14 days Toxicology research.A total of 30 Kunming mice were randomly divided into 6 groups and were divided into 2 batches for experiments.The results of the two experiments were consistent: The Kunming mice had no significant changes in body weight after being treated with KT to different concentrations for 14 days, Normal test indicators, heart, liver, lung, kidney and testis were no tissue distortion.