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目的 调查河南省0～6岁儿童脑性瘫痪(CP)的患病率、临床类型、相关病因及合并症的状况。方法 2001年1～12月,采用随机整群抽样方法,对河南省郑州市(金水区、二七区、邙山区)、洛阳市涧西区、济源市、原阳县、新野县、唐河县、太康县、虞城县10个市、区、县1995年1月1日至2000年12月31日出生的0～6岁儿童进行了调查。应用SPSS 10.0软件,进行统计学分析。结果 共调查0～6岁儿童434920人,男231111人,女203809人,男:女=1.13:1;发现CP患儿582例,男374例,女208例,男:女=1.80:1;患病率1.07‰～2.38‰,平均患病率为1.58‰。CP的各种类型中,痉挛型最多见,为331例(56.9％),肌张力低下型123例(21.1％),混合型44例(7.6％),强直型39例(6.7％),共济失调型31例(5.3％),震颤型8例(1.4％),手足徐动型6例(1.0％)CP的病因学调查中,以出生时窒息及缺氧缺血性脑病为多见,占38.3％(223例),双胎20.1％(117例),早产和(或)低体重16.8％(98例),母孕早期感染11.9％(69例),脑出血9.3％(54例)。以上均是引起CP的明显相关因素(与健康儿童组对比,均产<0.05),而新生儿期高胆红素血症、感染及胎粪吸入等,与CP的发生无明显相关性(P>0.05)。CT或MRI检查异常率70.0％(297/424例)。有合并症者占67.8％(394例),合并智力低下者49.0％(285例),语?
Objective To investigate the prevalence, clinical types, related etiology and complications of cerebral palsy (CP) in children aged 0 ~ 6 years in Henan Province. Methods From January to December 2001, a random cluster sampling method was used to study the effects of random sampling on Zhengzhou City (Jinshui District, Erqi District, Dangshan District), Jianxi District, Jiyuan City, Yuanyang County, Xinye County, Tanghe County , Taikang County, Yucheng County 10 cities, districts and counties from January 1, 1995 to December 31, 2000 born 0 to 6-year-old children were investigated. SPSS 10.0 software was used for statistical analysis. Results A total of 434920 children aged 0-6 years were enrolled. There were 231111 males and 203809 females with male: female = 1.13: 1. 582 children with CP were found, including 374 males and 208 females, with a male: 1.80: 1; The prevalence of 1.07 ‰ ~ 2.38 ‰, the average prevalence was 1.58 ‰. Among the various types of CP, spasticity was most common in 331 (56.9%), 123 (21.1%) with hypotonia, 44 (7.6%) in mixed and 39 (6.7%) in tonic There were 31 (5.3%) cases of ataxia, 8 cases of tremor (1.4%), and 6 cases of hand-foot-suturing (1.0%). In the etiological investigation of CP, asphyxia at birth and hypoxic-ischemic encephalopathy , Accounting for 38.3% (223 cases), 20.1% (117 cases), premature birth and / or low body weight 16.8% (98 cases), early motherhood infection 11.9% (69 cases), intracerebral hemorrhage 9.3% ). The above were the significant factors that caused CP (all <0.05), while neonatal hyperbilirubinemia, infection and meconium aspiration had no significant correlation with the occurrence of CP (P > 0.05). The abnormal rate of CT or MRI examination was 70.0% (297/424 cases). 67.8% (394 cases) with comorbidity, 49.0% (285 cases) with mental retardation, language