论文部分内容阅读
目的了解无偿献血人群人巨细胞病毒(HCMV)感染情况,探讨临床特殊用血进行HCMV抗体检测的必要性。方法采用ELISA吸附试验(ELISA)检测3 696份检验合格血液中的HCMV-IgM抗体和HCMV-IgG抗体,并对检测结果按献血者不同职业、年龄、性别进行比较分析。结果南昌市合格无偿献血人群HCMV-IgG的阳性率为89.72%,HCMV-IgM的阳性率为2.62%;IgG阳性率比较,男性92.65%,女性85.11%;不同年龄段相比较IgG阳性率18～30岁为82.96%,31～43岁为94.87%,44～55岁为98.80%,随着年龄增长阳性率逐渐升高,而IgM阳性率无统计学意义;不同职业相比较IgG阳性率高低顺序为:工人(99.24%)>农民(97.35%)>普通市民(94.45%)>公务员(94.32%)>大学生(82.70%)>军人(70.27%),IgM阳性率高低顺序为:农民(7.20%)>工人(5.49%)>普通市民(2.80%)>公务员(2.27%)>大学生(0.63%)>军人(0.19%)。结论南昌市无偿献血人群活动性HCMV感染率较低,低免疫力人群临床输血前有进行HCMV-IgM筛选的必要。
Objective To understand the human cytomegalovirus (HCMV) infection in unpaid blood donors and to explore the necessity of detecting HCMV antibodies in clinical special blood. Methods HCMV-IgM and HCMV-IgG antibodies in 3 696 blood samples were tested by ELISA. The results of blood test were compared by different occupations, ages and sexes of blood donors. Results The positive rate of HCMV-IgG was 89.72% and the positive rate of HCMV-IgM was 2.62% in Nanchang. The positive rate of IgG was 92.65% in males and 85.11% in females. The positive rate of HCMV-IgM in different age groups was 18 ~ The age of 30 years was 82.96%, the age of 31 ~ 43 was 94.87% and the age of 44 ~ 55 was 98.80%. With the increase of age, the positive rate of IgM gradually increased while the positive rate of IgM was not statistically significant. The average positive rate of IgM was: peasants (7.20%), peasants (97.35%), ordinary citizens (94.45%), civil servants (94.32%), college students (82.70%) and military personnel (70.27% )> Workers (5.49%)> ordinary citizens (2.80%)> civil servants (2.27%)> college students (0.63%)> soldiers (0.19%). Conclusion The prevalence of active HCMV in blood donors in Nanchang is relatively low. It is necessary to screen for HCMV-IgM before clinical transfusion in low-immunity groups.