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选取2013年2月~2014年3月我院经临床检查诊断为幽门螺杆菌(Hp)感染患者102例,随机分为对照组和观察组各51例,对照组患者采用四联疗法进行治疗,观察组患者在四联疗法治疗的基础上外加黄芪颗粒联合治疗,治疗后通过13C-尿素呼气试验对其治疗情况进行评价分析。结果两组患者在治疗后临床症状均得以好转,对照组中根除例数40例,根除率为78.4%,治疗期间出现恶心、呕吐、便秘、腹泻等不良反应8例;观察组中根除47例,根除率为92.2%,治疗期间出现不良反应6例,两组间比较差异有统计学意义(P<0.05)。在除Hp感染疾病的治疗过程中,采用四联疗法联合黄芪颗粒治疗效果显著,可有效改善患者临床症状,提高Hp根除率,同时不良反应少,值得在临床上进行推广和应用。
A total of 102 patients with Helicobacter pylori (Hp) infection who were clinically diagnosed in our hospital from February 2013 to March 2014 were randomly divided into control group and observation group (n = 51). Patients in the control group were treated with quadruple therapy The observation group was treated with combination of Astragalus membranaceus and Astragalus membranaceus on the basis of quadruple therapy. After treatment, the treatment was evaluated by 13C-urea breath test. Results The clinical symptoms of both groups were improved after treatment. In the control group, 40 cases were eradicated and the eradication rate was 78.4%. Eight cases of nausea, vomiting, constipation, diarrhea and other adverse reactions occurred during the treatment. In the observation group, 47 cases were eradicated , Eradication rate was 92.2%. There were 6 adverse reactions during the treatment. The difference between the two groups was statistically significant (P <0.05). In addition to Hp infection in the treatment of disease, the combination of quadruple therapy with Astragalus Granules significant effect, which can effectively improve the clinical symptoms and improve the Hp eradication rate, with fewer adverse reactions, it is worth in the clinical promotion and application.