随着人民生活水平的提高 ,肥胖已成为全球越来越普遍的现象。近年的研究表明 ,肥胖是由特定的生化因子引起的一系列进食调控和能量代谢紊乱而导致的疾病 ,与遗传、环境、膳食结构等多种因素有关 ,其中基因是主要的决定因素[1] 。已知肥胖与糖尿病、心血管疾病、高血压、高脂血? With the improvement of people’s living standards, obesity has become an increasingly common phenomenon in the world. Recent studies have shown that obesity is a series of diseases caused by a series of eating regulation and energy metabolism disorders caused by specific biochemical factors and is related to many factors such as genetics, environment and dietary structure, of which genes are the major determinants [1] . Known obesity and diabetes, cardiovascular disease, hypertension, hyperlipidemia?