Zika virus infection is a new emerging viral disease that becomes the present public health threat. At present, this infection can be seen in several countries. The clinical presentation of this infection is a dengue-like illness. Nevertheless, the new information shows that the disease can be sexually transmitted and transplacentally transmitted. In addition, the recent evidence from the recent epidemic in South America shows that the infection in pregnancy can cause neonatal neurological defect. In this short review, the author summarizes and presents interesting data on clinical features of this new emerging infection. At present, this infection can be seen in several countries. The clinical presentation of this infection is a dengue-like illness. Nevertheless, the new information shows that the In addition, the recent evidence from the recent epidemic in South America shows that the infection in pregnancy can cause neonatal neurological defect. In this short review, the author summarizes and presents interesting data on clinical features of this new emerging infection.